|Noah Webster's Dictionary|
1. (n.) Hopelessness; despondency; discouragement.
2. (v. t.) To give up as beyond hope or expectation; to despair of.
3. (v. t.) To cause to despair.
4. (n.) Loss of hope; utter hopelessness; complete despondency.
5. (n.) That which is despaired of.
Int. Standard Bible Encyclopedia
de-spar': The substantive only in 2 Corinthians 4:8, "perplexed, but not in (the Revised Version (British and American) "yet not unto") despair," literally, "being at a loss, but not utterly at a loss." "Unto despair" here conveys the force of the Greek prefix ex ("utterly," "out and out"). Desperate, in Job 6:26 Isaiah 17:11. In the latter instance, the Hebrew adjective is derived from a verb = "to be sick," and the literally, rendering would be "incurable" (compare Job 34:6, "my wound is incurable"). Desperately in Jeremiah 17:9 the King James Version, where the heart is said to be "desperately (i.e. incurably) wicked" or "sick."
Despair (23 Occurrences)
2 Corinthians 1:8 For we don't desire to have you uninformed, brothers, concerning our affliction which happened to us in Asia, that we were weighed down exceedingly, beyond our power, so much that we despaired even of life. (Root in WEB KJV ASV DBY WBS YLT NAS RSV NIV)
2 Corinthians 2:7 So that you may now take the opposite course, and forgive him rather and comfort him, for fear he should perhaps be driven to despair by his excess of grief. (WEY)
2 Corinthians 4:8 We are pressed on every side, yet not crushed; perplexed, yet not to despair; (WEB KJV ASV WBS YLT NAS RSV NIV)
Deuteronomy 28:65 Among these nations you shall find no ease, and there shall be no rest for the sole of your foot: but Yahweh will give you there a trembling heart, and failing of eyes, and pining of soul; (See NAS NIV)
1 Samuel 4:20 About the time of her death the women who stood by her said to her, "Don't be afraid; for you have brought forth a son." But she didn't answer, neither did she regard it. (See NIV)
1 Samuel 27:1 David said in his heart, "I shall now perish one day by the hand of Saul. There is nothing better for me than that I should escape into the land of the Philistines; and Saul will despair of me, to seek me any more in all the borders of Israel. So shall I escape out of his hand." (WEB KJV JPS ASV DBY WBS YLT NAS RSV)
Job 6:26 Do ye hold words to be an argument, but the speeches of one that is desperate to be wind? (See NAS RSV NIV)
Job 9:23 If the scourge kills suddenly, he will mock at the trial of the innocent. (See NAS NIV)
Job 24:22 Yet God preserves the mighty by his power. He rises up who has no assurance of life. (See RSV)
Job 41:25 When he raiseth himself up, the mighty are afraid: By reason of consternation they are beside themselves. (See JPS)
Psalms 42:5 Why are you in despair, my soul? Why are you disturbed within me? Hope in God! For I shall still praise him for the saving help of his presence. (WEB NAS)
Psalms 42:6 My God, my soul is in despair within me. Therefore I remember you from the land of the Jordan, the heights of Hermon, from the hill Mizar. (WEB NAS)
Psalms 42:11 Why are you in despair, my soul? Why are you disturbed within me? Hope in God! For I shall still praise him, the saving help of my countenance, and my God. (WEB NAS)
Psalms 43:5 Why are you in despair, my soul? Why are you disturbed within me? Hope in God! For I shall still praise him: my Savior, my helper, and my God. (WEB NAS)
Psalms 69:20 Reproach has broken my heart, and I am full of heaviness. I looked for some to take pity, but there was none; for comforters, but I found none. (See RSV)
Psalms 88:15 I am afflicted and ready to die from my youth up. While I suffer your terrors, I am distracted. (See NIV)
Ecclesiastes 2:20 Therefore I began to cause my heart to despair concerning all the labor in which I had labored under the sun. (WEB KJV JPS ASV DBY WBS YLT NAS RSV NIV)
Isaiah 19:9 And all the workers in linen thread, and those who make cotton cloth, will be put to shame. (See RSV NIV)
Isaiah 61:3 To give them a fair head-dress in place of dust, the oil of joy in place of the clothing of grief, praise in place of sorrow; so that they may be named trees of righteousness, the planting of the Lord, and so that he may have glory. (See NIV)
Jeremiah 17:16 And I hastened not from feeding after Thee, And the desperate day I have not desired, Thou -- Thou hast known, The produce of my lips, before Thy face it hath been, (See NIV)
Ezekiel 4:16 Moreover he said to me, Son of man, behold, I will break the staff of bread in Jerusalem: and they shall eat bread by weight, and with fearfulness; and they shall drink water by measure, and in dismay: (See NIV)
Ezekiel 7:27 The king doth become a mourner, And a prince putteth on desolation, And the hands of the people of the land are troubled, From their own way I deal with them, And with their own judgments I judge them, And they have known that I 'am' Jehovah!' (See RSV NIV)
Ezekiel 12:19 and thou hast said unto the people of the land, Thus said the Lord Jehovah concerning the inhabitants of Jerusalem, concerning the land of Israel: Their bread with fear they do eat, and their water with astonishment drink, because its land is desolate, because of its fulness, because of the violence of all who are dwelling in it. (See NIV)